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Berlin, Kenneth
One or more keywords matched the following items that are connected to Berlin, Kenneth
Item TypeName
Concept Structure-Activity Relationship
Academic Article Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity.
Academic Article Development of flexible-heteroarotinoids for kidney cancer.
Academic Article The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking.
Academic Article Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids.
Academic Article Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors.
Academic Article Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells.
Academic Article Novel heteroarotinoids as potential antagonists of Mycobacterium bovis BCG.
Academic Article Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis.
Academic Article Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line.
Academic Article Synthesis and biological evaluation of SHetA2 (NSC-721689) analogs against the ovarian cancer cell line A2780.
Academic Article Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase.
Academic Article Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships.
Academic Article Novel heteroarotinoids: synthesis and biological activity.
Academic Article Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase.
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  • Structure Activity Relationship